Differential Regulation of ERK1/2 and mTORC1 Through T1R1/T1R3 in MIN6 Cells

The MAPKs ERK1/2 respond to nutrients and other insulin secretagogues in pancreatic β-cells and mediate nutrient-dependent insulin gene transcription. Nutrients also stimulate the mechanistic target of rapamycin complex 1 (mTORC1) to regulate protein synthesis. We showed previously that activation o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Endocrinol
Prif Awduron: Wauson, Eric M., Guerra, Marcy L., Dyachok, Julia, McGlynn, Kathleen, Giles, Jennifer, Ross, Elliott M., Cobb, Melanie H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2015
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517997/
https://ncbi.nlm.nih.gov/pubmed/26168033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/ME.2014-1181
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