Curcumin-Mediated HDAC Inhibition Suppresses the DNA Damage Response and Contributes to Increased DNA Damage Sensitivity

Chemo- and radiotherapy cause multiple forms of DNA damage and lead to the death of cancer cells. Inhibitors of the DNA damage response are candidate drugs for use in combination therapies to increase the efficacy of such treatments. In this study, we show that curcumin, a plant polyphenol, sensitiz...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Wang, Shu-Huei, Lin, Pei-Ya, Chiu, Ya-Chen, Huang, Ju-Sui, Kuo, Yi-Tsen, Wu, Jen-Chine, Chen, Chin-Chuan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517890/
https://ncbi.nlm.nih.gov/pubmed/26218133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134110
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