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Spread of pathology in amyotrophic lateral sclerosis: assessment of phosphorylated TDP-43 along axonal pathways

INTRODUCTION: The progression of amyotrophic lateral sclerosis (ALS) through the brain has recently been staged using independent neuropathological and neuroimaging modalities. The two schemes tie into the concept of pathological spread through corticofugal axonal transmission that stems from observ...

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Pubblicato in:Acta Neuropathol Commun
Autori principali: Fatima, Manaal, Tan, Rachel, Halliday, Glenda M., Kril, Jillian J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517552/
https://ncbi.nlm.nih.gov/pubmed/26216351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0226-y
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