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Delicate conformational balance of the redox enzyme cytochrome P450cam

The energy landscapes of proteins are highly complex and can be influenced by changes in physical and chemical conditions under which the protein is studied. The redox enzyme cytochrome P450cam undergoes a multistep catalytic cycle wherein two electrons are transferred to the heme group and the enzy...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Skinner, Simon P., Liu, Wei-Min, Hiruma, Yoshitaka, Timmer, Monika, Blok, Anneloes, Hass, Mathias A. S., Ubbink, Marcellus
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517283/
https://ncbi.nlm.nih.gov/pubmed/26130807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502351112
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