Delicate conformational balance of the redox enzyme cytochrome P450cam

The energy landscapes of proteins are highly complex and can be influenced by changes in physical and chemical conditions under which the protein is studied. The redox enzyme cytochrome P450cam undergoes a multistep catalytic cycle wherein two electrons are transferred to the heme group and the enzy...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Skinner, Simon P., Liu, Wei-Min, Hiruma, Yoshitaka, Timmer, Monika, Blok, Anneloes, Hass, Mathias A. S., Ubbink, Marcellus
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517283/
https://ncbi.nlm.nih.gov/pubmed/26130807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502351112
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