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Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene-Based Ligands to Distinguish β-Amyloid or Tau Polymorphic Aggregates

The accumulation of protein aggregates is associated with many devastating neurodegenerative diseases and the existence of distinct aggregated morphotypes has been suggested to explain the heterogeneous phenotype reported for these diseases. Thus, the development of molecular probes able to distingu...

詳細記述

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書誌詳細
出版年:Chemistry
主要な著者: Klingstedt, Therése, Shirani, Hamid, Mahler, Jasmin, Wegenast-Braun, Bettina M, Nyström, Sofie, Goedert, Michel, Jucker, Mathias, Nilsson, K Peter R
フォーマット: Artigo
言語:Inglês
出版事項: WILEY-VCH Verlag 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517144/
https://ncbi.nlm.nih.gov/pubmed/26013403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201500556
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