The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice

Identification of fluorescent dyes that label the filamentous protein aggregates characteristic of neurodegenerative disease, such as β-amyloid and tau in Alzheimer's disease, in a live cell culture system has previously been a major hurdle. Here we show that pentameric formyl thiophene acetic...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Front Neurosci
Main Authors: Brelstaff, Jack, Ossola, Bernardino, Neher, Jonas J., Klingstedt, Therése, Nilsson, K. Peter R., Goedert, Michel, Spillantini, Maria Grazia, Tolkovsky, Aviva M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Psychiatry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448042/
https://ncbi.nlm.nih.gov/pubmed/26074756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00184
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker