Blocking neutrophil integrin activation prevents ischemia–reperfusion injury

Neutrophil recruitment, mediated by β2 integrins, combats pyogenic infections but also plays a key role in ischemia–reperfusion injury and other inflammatory disorders. Talin induces allosteric rearrangements in integrins that increase affinity for ligands (activation). Talin also links integrins to...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Yago, Tadayuki, Petrich, Brian G., Zhang, Nan, Liu, Zhenghui, Shao, Bojing, Ginsberg, Mark H., McEver, Rodger P.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516797/
https://ncbi.nlm.nih.gov/pubmed/26169939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20142358
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki