Numerical chromosomal instability mediates susceptibility to radiation treatment

The exquisite sensitivity of mitotic cancer cells to ionizing radiation (IR) underlies an important rationale for the widely used fractionated radiation therapy. However, the mechanism for this cell cycle-dependent vulnerability is unknown. Here we show that treatment with IR leads to mitotic chromo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Bakhoum, Samuel F., Kabeche, Lilian, Wood, Matthew D., Laucius, Christopher D., Qu, Dian, Laughney, Ashley M., Reynolds, Gloria E., Louie, Raymond J., Phillips, Joanna, Chan, Denise A., Zaki, Bassem I., Murnane, John P., Petritsch, Claudia, Compton, Duane A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516720/
https://ncbi.nlm.nih.gov/pubmed/25606712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6990
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados