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Tamoxifen regulation of sphingolipid metabolism—therapeutic implications
Tamoxifen, a triphenylethylene antiestrogen and one of the first-line endocrine therapies used to treat estrogen receptor-positive breast cancer, has a number of interesting, off-target effects, and among these is the inhibition of sphingolipid metabolism. More specifically, tamoxifen inhibits ceram...
Gorde:
| Argitaratua izan da: | Biochim Biophys Acta |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516673/ https://ncbi.nlm.nih.gov/pubmed/25964209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2015.05.001 |
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