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Ceramide Formation Mediated by Acid Sphingomyelinase Facilitates Endosomal Escape of Caliciviruses

Our recent results demonstrated that bile acids facilitate virus escape from the endosomes into the cytoplasm for successful replication of porcine enteric calicivirus (PEC). We report a novel finding that bile acids can be substituted by cold treatment for endosomal escape and virus replication. Th...

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Bibliographische Detailangaben
Veröffentlicht in:Virology
Hauptverfasser: Shivanna, Vinay, Kim, Yunjeong, Chang, Kyeong-Ok
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516657/
https://ncbi.nlm.nih.gov/pubmed/25985440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.04.022
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