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Ceramide Formation Mediated by Acid Sphingomyelinase Facilitates Endosomal Escape of Caliciviruses

Our recent results demonstrated that bile acids facilitate virus escape from the endosomes into the cytoplasm for successful replication of porcine enteric calicivirus (PEC). We report a novel finding that bile acids can be substituted by cold treatment for endosomal escape and virus replication. Th...

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Bibliografske podrobnosti
izdano v:Virology
Main Authors: Shivanna, Vinay, Kim, Yunjeong, Chang, Kyeong-Ok
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516657/
https://ncbi.nlm.nih.gov/pubmed/25985440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.04.022
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