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Ceramide Formation Mediated by Acid Sphingomyelinase Facilitates Endosomal Escape of Caliciviruses

Our recent results demonstrated that bile acids facilitate virus escape from the endosomes into the cytoplasm for successful replication of porcine enteric calicivirus (PEC). We report a novel finding that bile acids can be substituted by cold treatment for endosomal escape and virus replication. Th...

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Bibliographic Details
Published in:Virology
Main Authors: Shivanna, Vinay, Kim, Yunjeong, Chang, Kyeong-Ok
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516657/
https://ncbi.nlm.nih.gov/pubmed/25985440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.04.022
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