Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

Directed differentiation of human pluripotent stem cells into functional insulin-producing beta-like cells holds great promise for cell replacement therapy for patients suffering from diabetes. This approach also offers the unique opportunity to study otherwise inaccessible aspects of human beta cel...

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Publicado en:EMBO J
Main Authors: Russ, Holger A, Parent, Audrey V, Ringler, Jennifer J, Hennings, Thomas G, Nair, Gopika G, Shveygert, Mayya, Guo, Tingxia, Puri, Sapna, Haataja, Leena, Cirulli, Vincenzo, Blelloch, Robert, Szot, Greg L, Arvan, Peter, Hebrok, Matthias
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Ltd 2015
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516429/
https://ncbi.nlm.nih.gov/pubmed/25908839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591058
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