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Islet formation in mice and men: Lessons for the generation of functional insulin-producing β cells from human pluripotent stem cells

The Islets of Langerhans are crucial ‘micro-organs’ embedded in the glandular exocrine pancreas that regulate nutrient metabolism. They not only synthesize, but also secrete endocrine hormones in a modulated fashion in response to physiologic metabolic demand. These highly sophisticated structures w...

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Detalhes bibliográficos
Publicado no:Curr Opin Genet Dev
Main Authors: Nair, Gopika, Hebrok, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523641/
https://ncbi.nlm.nih.gov/pubmed/25909383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2015.03.004
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