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ENDOR spectroscopy and DFT calculations: evidence for the hydrogen bond network within α2 in the PCET of E. coli ribonucleotide reductase
E.coli class I ribonucleotide reductase (RNR) catalyzes the conversion of nucleotides to deoxynucleotides and is composed of two subunits: α2 and β2. β2 contains a stable di-iron tyrosyl radical (Y(122)(•)) cofactor required to generate a thiyl radical (C(439)(•)) in α2 over a distance of 35 Å, whic...
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| Vydáno v: | J Am Chem Soc |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516058/ https://ncbi.nlm.nih.gov/pubmed/23072506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3071682 |
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