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Timing of eculizumab therapy for C3 glomerulonephritis
Eculizumab is an anti-C5 antibody that inhibits C5 cleavage and prevents the generation of the terminal complement complex C5b-9. Eculizumab is licensed to treat paroxysmal nocturnal haemoglobinuria or atypical haemolytic uraemic syndrome (aHUS). Clinical trials are ongoing for C3 glomerulopathy. Gi...
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| Published in: | Clin Kidney J |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4515909/ https://ncbi.nlm.nih.gov/pubmed/26251715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfv065 |
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