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Eculizumab-induced reversal of dialysis-dependent kidney failure from C3 glomerulonephritis

C3 glomerulopathy (C3G) is characterized by C3 deposits with minimal immunoglobulin deposition caused by alternative complement pathway dysregulation. Unfortunately, no therapeutic intervention has consistently improved outcomes for patients with C3G. Eculizumab, a monoclonal antibody to C5, is curr...

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Detalhes bibliográficos
Publicado no:Clin Kidney J
Main Authors: Inman, Melissa, Prater, Ginnie, Fatima, Huma, Wallace, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515899/
https://ncbi.nlm.nih.gov/pubmed/26251714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfv044
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