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Eculizumab and Recurrent C3 Glomerulonephritis
BACKGROUND AND OBJECTIVES: Hyperactivity of the alternative complement pathway is the principle defect in the C3 glomerulopathies (C3G). Eculizumab, a monoclonal antibody that binds to C5 to prevent formation of the membrane attack complex, has been shown to be beneficial in some patients with this...
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| Udgivet i: | Pediatr Nephrol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4428658/ https://ncbi.nlm.nih.gov/pubmed/23689905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-013-2503-y |
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