C3 glomerulonephritis secondary to mutations in factors H and I: rapid recurrence in deceased donor kidney transplant effectively treated with eculizumab

BACKGROUND: C3 glomerulonephritis (C3GN) is caused by alternate complement pathway over-activation. It frequently progresses to end-stage renal disease, recurs in two-thirds of transplants and in half of these cases progresses to allograft loss. There is currently no proven treatment for C3GN. CASE...

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Bibliografski detalji
Izdano u:Nephrol Dial Transplant
Glavni autori: Garg, Neetika, Zhang, Yuzhou, Nicholson-Weller, Anne, Khankin, Eliyahu V, Borsa, Nicolò Ghiringhelli, Meyer, Nicole C, McDermott, Susan, Stillman, Isaac E, Rennke, Helmut G, Smith, Richard J, Pavlakis, Martha
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275145/
https://ncbi.nlm.nih.gov/pubmed/29370420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfx369
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