Diazoxide Cardioprotection Is Independent of Adenosine Triphosphate-Sensitive Potassium Channel Kir6.1 Subunit in Response to Stress

BACKGROUND: The sarcolemmal adenosine triphosphate-sensitive potassium channel (sK(ATP)), composed primarily of Kir6.2 and SUR2A subunits, has been implicated in cardiac myocyte volume regulation during stress; however, it is not involved in cardioprotection by the K(ATP) channel opener diazoxide. P...

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Detalhes bibliográficos
Publicado no:J Am Coll Surg
Principais autores: Henn, Matthew C, Janjua, M Burhan, Zhang, Haixia, Kanter, Evelyn M, Makepeace, Carol M, Schuessler, Richard B, Nichols, Colin G, Lawton, Jennifer S
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515177/
https://ncbi.nlm.nih.gov/pubmed/25872691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2015.02.014
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