Increased tolerance to stress in cardiac expressed gain-of-function of adenosine triphosphate–sensitive potassium channel subunit Kir6.1

BACKGROUND: The adenosine triphosphate–sensitive potassium (K(ATP)) channel opener diazoxide (DZX) prevents myocyte volume derangement and reduced contractility secondary to stress. K(ATP) channels are composed of pore-forming (Kir6.1 or Kir6.2) and regulatory (sulfonylurea receptor, SUR1 or SUR2) s...

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Pubblicato in:J Surg Res
Autori principali: Henn, Matthew C., Janjua, M. Burhan, Zhang, Haixia, Kanter, Evelyn M., Makepeace, Carol M., Schuessler, Richard B., Nichols, Colin G., Lawton, Jennifer S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927332/
https://ncbi.nlm.nih.gov/pubmed/27884343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2016.08.043
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