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Cardioprotective Benefits of Adenosine Triphosphate: Sensitive Potassium Channel Opener Diazoxide Are Lost with Administration after the Onset of Stress in Mouse and Human Myocytes

BACKGROUND: Adenosine triphosphate - sensitive (K(ATP)) potassium channel opener diazoxide (DZX) maintains myocyte volume and contractility during stress via an unknown mechanism when administered at the onset of stress. This study was performed to investigate the cardioprotective potential of DZX w...

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Bibliografiske detaljer
Main Authors: Janjua, M Burhan, Makepeace, Carol M, Anastacio, Melissa M, Schuessler, Richard B, Nichols, Colin G, Lawton, Jennifer S
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197936/
https://ncbi.nlm.nih.gov/pubmed/25158912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2014.05.010
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