DAZL regulates Tet1 translation in murine embryonic stem cells

Embryonic stem cell (ESC) cultures display a heterogeneous gene expression profile, ranging from a pristine naïve pluripotent state to a primed epiblast state. Addition of inhibitors of GSK3β and MEK (so-called 2i conditions) pushes ESC cultures toward a more homogeneous naïve pluripotent state, but...

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Udgivet i:EMBO Rep
Main Authors: Welling, Maaike, Chen, Hsu-Hsin, Muñoz, Javier, Musheev, Michael U, Kester, Lennart, Junker, Jan Philipp, Mischerikow, Nikolai, Arbab, Mandana, Kuijk, Ewart, Silberstein, Lev, Kharchenko, Peter V, Geens, Mieke, Niehrs, Christof, van de Velde, Hilde, van Oudenaarden, Alexander, Heck, Albert JR, Geijsen, Niels
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
Fag:
Scientific Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515119/
https://ncbi.nlm.nih.gov/pubmed/26077710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540538
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