DAZL regulates Tet1 translation in murine embryonic stem cells

Embryonic stem cell (ESC) cultures display a heterogeneous gene expression profile, ranging from a pristine naïve pluripotent state to a primed epiblast state. Addition of inhibitors of GSK3β and MEK (so-called 2i conditions) pushes ESC cultures toward a more homogeneous naïve pluripotent state, but...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Welling, Maaike, Chen, Hsu-Hsin, Muñoz, Javier, Musheev, Michael U, Kester, Lennart, Junker, Jan Philipp, Mischerikow, Nikolai, Arbab, Mandana, Kuijk, Ewart, Silberstein, Lev, Kharchenko, Peter V, Geens, Mieke, Niehrs, Christof, van de Velde, Hilde, van Oudenaarden, Alexander, Heck, Albert JR, Geijsen, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515119/
https://ncbi.nlm.nih.gov/pubmed/26077710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540538
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