DAZL Limits Pluripotency, Differentiation, and Apoptosis in Developing Primordial Germ Cells

The scarcity of primordial germ cells (PGCs) in the developing mammalian embryo hampers robust biochemical analysis of the processes that underlie early germ cell formation. Here, we demonstrate that DAZL, a germ cell-specific RNA binding protein, is a robust PGC marker during in vitro germ cell dev...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Chen, Hsu-Hsin, Welling, Maaike, Bloch, Donald B., Muñoz, Javier, Mientjes, Edwin, Chen, Xinjie, Tramp, Cody, Wu, Jie, Yabuuchi, Akiko, Chou, Yu-Fen, Buecker, Christa, Krainer, Adrian, Willemsen, Rob, Heck, Albert J., Geijsen, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235140/
https://ncbi.nlm.nih.gov/pubmed/25418731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.09.003
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