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Stem cells are resistant to TRAIL receptor-mediated apoptosis

New therapeutic approaches aim to eradicate tumours by expression of tumouricidal proteins in the tumour stroma. One such anti-neoplastic protein is tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) because it induces apoptosis in cancerous cells, but not in non-transformed cells. Ste...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Szegezdi, Eva, O’Reilly, Aoife, Davy, Yeung, Vawda, Reaz, Taylor, Deanna L, Murphy, Mary, Samali, Afshin, Mehmet, Huseyin
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515056/
https://ncbi.nlm.nih.gov/pubmed/19604313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00522.x
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