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The Proteasome Inhibitor Bortezomib Sensitizes AML with Myelomonocytic Differentiation to TRAIL Mediated Apoptosis

Acute myeloid leukemia (AML) is an aggressive stem cell malignancy that is difficult to treat. There are limitations to the current treatment regimes especially after disease relapse, and therefore new therapeutic agents are urgently required which can overcome drug resistance whilst avoiding unnece...

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Detalhes bibliográficos
Main Authors: van Dijk, Marianne, Murphy, Eoin, Morrell, Ruth, Knapper, Steven, O'Dwyer, Michael, Samali, Afshin, Szegezdi, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756416/
https://ncbi.nlm.nih.gov/pubmed/24212664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers3011329
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