Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis on binding to its receptors, death receptor 4 and 5 (DR4, DR5). TRAIL can also activate c-Jun N-terminal kinase (JNK) through the adaptor molecules, TNF receptor-associated factor 2 (TRAF2) and receptor-interacting pr...

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Hlavní autoři: Mahalingam, D, Keane, M, Pirianov, G, Mehmet, H, Samali, A, Szegezdi, E
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
Translational Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694422/
https://ncbi.nlm.nih.gov/pubmed/19352384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605021
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