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Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells

BACKGROUND: Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) induces tumour cell apoptosis by binding to death receptor 4 (DR4) and DR5. DR4 and DR5 activation however can also induce inflammatory and pro-survival signalling. It is not known how these different cellular responses are...

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Detalhes bibliográficos
Main Authors: Mahalingam, D, Natoni, A, Keane, M, Samali, A, Szegezdi, E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837577/
https://ncbi.nlm.nih.gov/pubmed/20087343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605545
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