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SPARSE: quadratic time simultaneous alignment and folding of RNAs without sequence-based heuristics
Motivation: RNA-Seq experiments have revealed a multitude of novel ncRNAs. The gold standard for their analysis based on simultaneous alignment and folding suffers from extreme time complexity of [Formula: see text]. Subsequently, numerous faster ‘Sankoff-style’ approaches have been suggested. Commo...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4514930/ https://ncbi.nlm.nih.gov/pubmed/25838465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv185 |
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