Fast and accurate structure probability estimation for simultaneous alignment and folding of RNAs with Markov chains

MOTIVATION: Simultaneous alignment and folding (SA&F) of RNAs is the indispensable gold standard for inferring the structure of non-coding RNAs and their general analysis. The original algorithm, proposed by Sankoff, solves the theoretical problem exactly with a complexity of [Formula: see text]...

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Bibliografiske detaljer
Udgivet i:Algorithms Mol Biol
Main Authors: Miladi, Milad, Raden, Martin, Will, Sebastian, Backofen, Rolf
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666477/
https://ncbi.nlm.nih.gov/pubmed/33292340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13015-020-00179-w
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