PPARγ Ligands Attenuate Hypoxia-Induced Proliferation in Human Pulmonary Artery Smooth Muscle Cells through Modulation of MicroRNA-21

Pulmonary hypertension (PH) is a progressive and often fatal disorder whose pathogenesis involves pulmonary artery smooth muscle cell (PASMC) proliferation. Although modern PH therapies have significantly improved survival, continued progress rests on the discovery of novel therapies and molecular t...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Green, David E., Murphy, Tamara C., Kang, Bum-Yong, Searles, Charles D., Hart, C. Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514882/
https://ncbi.nlm.nih.gov/pubmed/26208095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133391
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