PPARγ Ligands Attenuate Hypoxia-Induced Proliferation in Human Pulmonary Artery Smooth Muscle Cells through Modulation of MicroRNA-21

Pulmonary hypertension (PH) is a progressive and often fatal disorder whose pathogenesis involves pulmonary artery smooth muscle cell (PASMC) proliferation. Although modern PH therapies have significantly improved survival, continued progress rests on the discovery of novel therapies and molecular t...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Green, David E., Murphy, Tamara C., Kang, Bum-Yong, Searles, Charles D., Hart, C. Michael
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514882/
https://ncbi.nlm.nih.gov/pubmed/26208095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133391
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