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PPARγ Ligands Attenuate Hypoxia-Induced Proliferation in Human Pulmonary Artery Smooth Muscle Cells through Modulation of MicroRNA-21

Pulmonary hypertension (PH) is a progressive and often fatal disorder whose pathogenesis involves pulmonary artery smooth muscle cell (PASMC) proliferation. Although modern PH therapies have significantly improved survival, continued progress rests on the discovery of novel therapies and molecular t...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Green, David E., Murphy, Tamara C., Kang, Bum-Yong, Searles, Charles D., Hart, C. Michael
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514882/
https://ncbi.nlm.nih.gov/pubmed/26208095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133391
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