Hypoxia Mediates Mutual Repression between microRNA-27a and PPARγ in the Pulmonary Vasculature

Pulmonary hypertension (PH) is a serious disorder that causes significant morbidity and mortality. The pathogenesis of PH involves complex derangements in multiple pathways including reductions in peroxisome proliferator-activated receptor gamma (PPARγ). Hypoxia, a common PH stimulus, reduces PPARγ...

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Autors principals: Kang, Bum-Yong, Park, Kathy K., Green, David E., Bijli, Kaiser M., Searles, Charles D., Sutliff, Roy L., Hart, C. Michael
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828382/
https://ncbi.nlm.nih.gov/pubmed/24244514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079503
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