Additive neuroprotection of a 20-HETE inhibitor with delayed therapeutic hypothermia after hypoxia-ischemia in neonatal piglets

The severity of perinatal hypoxia-ischemia and the delay in initiating therapeutic hypothermia limit the efficacy of hypothermia. After hypoxia-ischemia in neonatal piglets, the arachidonic acid metabolite, 20-hydroxyeicosatetraenoic acid (20-HETE), has been found to contribute to oxidative stress a...

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Detalhes bibliográficos
Publicado no:Dev Neurosci
Main Authors: Zhu, Junchao, Wang, Bing, Lee, Jeong-Hoo, Armstrong, Jillian S., Kulikowicz, Ewa, Bhalala, Utpal S., Martin, Lee J., Koehler, Raymond C., Yang, Zeng-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514546/
https://ncbi.nlm.nih.gov/pubmed/25721266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000369007
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