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Early Antioxidant Treatment and Delayed Hypothermia After Hypoxia-Ischemia Have No Additive Neuroprotection in Newborn Pigs

BACKGROUND: The implementation and clinical efficacy of hypothermia in neonatal hypoxic-ischemic (HI) encephalopathy are limited, in part, by the delay in instituting hypothermia and access to equipment. In a piglet model of HI, half of the neurons in putamen already showed ischemic cytopathology by...

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Detalhes bibliográficos
Main Authors: Ni, Xinli, Yang, Zeng-Jin, Wang, Bing, Carter, Erin L., Larson, Abby C., Martin, Lee J., Koehler, Raymond C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425722/
https://ncbi.nlm.nih.gov/pubmed/22745113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e31825d3600
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