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Neuroprotective effect of acid-sensing ion channel inhibitor psalmotoxin-1 after hypoxia-ischemia in newborn piglet striatum

Na(+), Ca(2+)- permeable acid-sensing ion channel 1a (ASIC1a) is involved in the pathophysiologic process of adult focal brain ischemia. However, little is known about its role in the pathogenesis of global cerebral ischemia or newborn hypoxia-ischemia (H-I). Here, using a newborn piglet model of as...

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Detalhes bibliográficos
Main Authors: Yang, Zeng-Jin, Ni, Xinli, Carter, Erin L, Kibler, Kathleen, Martin, Lee J, Koehler, Raymond C
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116689/
https://ncbi.nlm.nih.gov/pubmed/21558004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.04.018
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