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The in vivo dynamics of antigenic variation in Trypanosoma brucei

Trypanosoma brucei, a causative agent of African Sleeping Sickness, constantly changes its dense variant surface glycoprotein (VSG) coat to avoid elimination by the immune system of its mammalian host, using an extensive repertoire of dedicated genes. However, the dynamics of VSG expression in T. br...

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Bibliographic Details
Published in:Science
Main Authors: Mugnier, Monica R., Cross, George A. M., Papavasiliou, F. Nina
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514441/
https://ncbi.nlm.nih.gov/pubmed/25814582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa4502
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