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Hedgehog acyltransferase as a target in pancreatic ductal adenocarcinoma
Sonic Hedgehog (Shh) is abnormally expressed in pancreatic cancer and is associated with disease onset and progression. Inhibition of Shh signaling is thus an attractive clinical target for therapeutic intervention. Most efforts to block Shh signaling have focused on inhibitors of Smoothened, which...
Gespeichert in:
| Veröffentlicht in: | Oncogene |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4513646/ https://ncbi.nlm.nih.gov/pubmed/24469057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.575 |
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