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Hedgehog acyltransferase as a target in pancreatic ductal adenocarcinoma

Sonic Hedgehog (Shh) is abnormally expressed in pancreatic cancer and is associated with disease onset and progression. Inhibition of Shh signaling is thus an attractive clinical target for therapeutic intervention. Most efforts to block Shh signaling have focused on inhibitors of Smoothened, which...

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Bibliografski detalji
Izdano u:Oncogene
Glavni autori: Petrova, E, Matevossian, A, Resh, MD
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513646/
https://ncbi.nlm.nih.gov/pubmed/24469057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.575
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