Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS

The haloacid dehalogenase (HAD)-like enzymes comprise a large superfamily of phosphohydrolases present in all organisms. The Saccharomyces cerevisiae genome encodes at least 19 soluble HADs, including 10 uncharacterized proteins. Here, we biochemically characterized 13 yeast phosphatases from the HA...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Kuznetsova, Ekaterina, Nocek, Boguslaw, Brown, Greg, Makarova, Kira S., Flick, Robert, Wolf, Yuri I., Khusnutdinova, Anna, Evdokimova, Elena, Jin, Ke, Tan, Kemin, Hanson, Andrew D., Hasnain, Ghulam, Zallot, Rémi, de Crécy-Lagard, Valérie, Babu, Mohan, Savchenko, Alexei, Joachimiak, Andrzej, Edwards, Aled M., Koonin, Eugene V., Yakunin, Alexander F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Enzymology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513125/
https://ncbi.nlm.nih.gov/pubmed/26071590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.657916
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