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Diversification of Function in the Haloacid Dehalogenase Enzyme Superfamily: The Role of the Cap Domain in Hydrolytic Phosphorus-Carbon Bond Cleavage. ,

Phosphonatase functions in the 2-aminoethylphosphonate (AEP) degradation pathway of bacteria, catalyzing the hydrolysis of the C-P bond in phosphonoacetaldehyde (Pald) via formation of a bi-covalent Lys53ethylenamine/Asp12 aspartylphosphate intermediate. Because phosphonatase is a member of the halo...

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Detalhes bibliográficos
Main Authors: Lahiri, Sushmita D., Zhang, Guofeng, Dunaway-Mariano, Debra, Allen, Karen N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941675/
https://ncbi.nlm.nih.gov/pubmed/17070898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2006.09.007
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