Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS

The haloacid dehalogenase (HAD)-like enzymes comprise a large superfamily of phosphohydrolases present in all organisms. The Saccharomyces cerevisiae genome encodes at least 19 soluble HADs, including 10 uncharacterized proteins. Here, we biochemically characterized 13 yeast phosphatases from the HA...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kuznetsova, Ekaterina, Nocek, Boguslaw, Brown, Greg, Makarova, Kira S., Flick, Robert, Wolf, Yuri I., Khusnutdinova, Anna, Evdokimova, Elena, Jin, Ke, Tan, Kemin, Hanson, Andrew D., Hasnain, Ghulam, Zallot, Rémi, de Crécy-Lagard, Valérie, Babu, Mohan, Savchenko, Alexei, Joachimiak, Andrzej, Edwards, Aled M., Koonin, Eugene V., Yakunin, Alexander F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513125/
https://ncbi.nlm.nih.gov/pubmed/26071590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.657916
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