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Caspase 3 inactivation protects against hepatic cell death and ameliorates fibrogenesis in a diet induced NASH model
BACKGROUND/AIMS: Hepatocyte cell death is a key feature of nonalcoholic steohepatitis (NASH). As the contribution of specific caspases remains unclear, our aim was to ascertain the effect of caspase 3 suppression on liver injury and fibrogenesis. METHODS: C57BL/6 wild-type (WT), and caspase 3 knock...
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| Udgivet i: | Dig Dis Sci |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4512760/ https://ncbi.nlm.nih.gov/pubmed/24795036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-014-3167-6 |
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