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Aberrant regulation of the LIN28A/LIN28B and let-7 loop in human malignant tumors and its effects on the hallmarks of cancer

RNA binding proteins (RBPs) and microRNAs (miRNAs) are two of the most important post-transcriptional regulators of gene expression, and their aberrant expression contributes to the development of human malignancies. Let-7, one of the most well-known tumor suppressors, is frequently down-regulated i...

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Podrobná bibliografie
Vydáno v:Mol Cancer
Hlavní autoři: Wang, Tianzhen, Wang, Guangyu, Hao, Dapeng, Liu, Xi, Wang, Dong, Ning, Ning, Li, Xiaobo
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512107/
https://ncbi.nlm.nih.gov/pubmed/26123544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0402-5
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