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Stepwise assembly of multiple Lin28 proteins on the terminal loop of let-7 miRNA precursors
Lin28 inhibits the biogenesis of let-7 miRNAs through direct interactions with let-7 precursors. Previous studies have described seemingly inconsistent Lin28 binding sites on pre-let-7 RNAs. Here, we reconcile these data by examining the binding mechanism of Lin28 to the terminal loop of pre-let-7g...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985620/ https://ncbi.nlm.nih.gov/pubmed/24452802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1391 |
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