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Importance of the NCp7-like domain in the recognition of pre-let-7g by the pluripotency factor Lin28

The pluripotency factor Lin28 is a highly conserved protein comprising a unique combination of RNA-binding motifs, an N-terminal cold-shock domain and a C-terminal region containing two retroviral-type CCHC zinc-binding domains. An important function of Lin28 is to inhibit the biogenesis of the let-...

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Bibliografiske detaljer
Main Authors: Desjardins, Alexandre, Yang, Ao, Bouvette, Jonathan, Omichinski, James G., Legault, Pascale
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287177/
https://ncbi.nlm.nih.gov/pubmed/22013165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr808
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