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Epigenetic Repression of CCDC37 and MAP1B Links Chronic Obstructive Pulmonary Disease to Lung Cancer

INTRODUCTION: Lung cancer and chronic obstructive pulmonary disease (COPD) share environmental risk factors. COPD also increases the risk of lung cancer; however, the molecular mechanisms are unclear. METHODS: An epigenome-wide association study of lung tumors and cancer-free lung tissue (CFLT) pair...

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Pubblicato in:J Thorac Oncol
Autori principali: Tessema, Mathewos, Yingling, Christin M., Picchi, Maria A., Wu, Guodong, Liu, Yushi, Weissfeld, Joel L., Siegfried, Jill M., Tesfaigzi, Yohannes, Belinsky, Steven A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511946/
https://ncbi.nlm.nih.gov/pubmed/26200272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000592
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