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Histone modifications predispose genome regions to breakage and translocation
Chromosome translocations are well-established hallmarks of cancer cells and often occur at nonrandom sites in the genome. The molecular features that define recurrent chromosome breakpoints are largely unknown. Using a combination of bioinformatics, biochemical analysis, and cell-based assays, we i...
Tallennettuna:
| Julkaisussa: | Genes Dev |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Cold Spring Harbor Laboratory Press
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4511214/ https://ncbi.nlm.nih.gov/pubmed/26104467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.262170.115 |
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