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Dual targeting of therapeutics to endothelial cells: collaborative enhancement of delivery and effect

Anchoring pharmacologic agents to the vascular lumen has the potential to modulate critical processes at the blood–tissue interface, avoiding many of the off-target effects of systemically circulating agents. We report a novel strategy for endothelial dual targeting of therapeutics, which both enhan...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Greineder, Colin F., Brenza, Jacob B., Carnemolla, Ronald, Zaitsev, Sergei, Hood, Elizabeth D., Pan, Daniel C., Ding, Bi-Sen, Esmon, Charles T., Chacko, Ann Marie, Muzykantov, Vladimir R.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511192/
https://ncbi.nlm.nih.gov/pubmed/25953848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-271213
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