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Cryo-EM structure of Hepatitis C virus IRES bound to the human ribosome at 3.9-Å resolution
Hepatitis C virus (HCV), a widespread human pathogen, is dependent on a highly structured 5′-untranslated region of its mRNA, referred to as internal ribosome entry site (IRES), for the translation of all of its proteins. The HCV IRES initiates translation by directly binding to the small ribosomal...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Pub. Group
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4510694/ https://ncbi.nlm.nih.gov/pubmed/26155016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8646 |
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