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Involvement of serotonin transporter extracellular loop 1 in serotonin binding and transport
Residues Tyr-110 through Gly-115 of serotonin transporter were replaced, one at a time, with cysteine. Of these mutants, only G113C retained full activity for transport, Q111C and N112C retained partial activity, but Y110C, G114C and G115C were inactive. Poor surface expression was at least partly r...
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| Publicado en: | Mol Membr Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4510095/ https://ncbi.nlm.nih.gov/pubmed/18307099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09687680701633257 |
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