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Serotonin Transporter Phosphorylation by cGMP-Dependent Protein Kinase Is Altered by a Mutation Associated with Obsessive–Compulsive Disorder
Human serotonin transporter (hSERT) activity expressed in HeLa cells was stimulated by agents that release nitric oxide, stimulate soluble guanylyl cyclase, or activate cGMP-dependent protein kinase (PKG). This stimulation was blocked by a PKG inhibitor. A naturally occurring mutation, I425V, associ...
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| Gepubliceerd in: | J Neurosci |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Society for Neuroscience
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6672823/ https://ncbi.nlm.nih.gov/pubmed/17913921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0034-07.2007 |
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